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Saturday, February 5, 2011

Feb. 4 - Brain's neurons found to communicate via electric fields

Dear Friends,
 
http://www.scienceagogo.com/news/20110102222950data_trunc_sys.shtml
 
Be Well.
 
David
 
3 February 2011

Brain's neurons found to communicate via electric fields
 by Kate Melville

Neurons in the brain had been thought to communicate exclusively via the physical connections that are known as synapses, but Caltech researchers say they have uncovered strong evidence that neurons also communicate with each other via weak electric fields, a finding that could help us understand how biophysics gives rise to cognition - the holy grail of neuroscience.

The new research, appearing in the journal Nature Neuroscience, explains how the brain is awash with electrical activity, and not just from the individual pings of single neurons communicating with each other. In fact, the brain is enveloped in countless overlapping electric fields, generated by the neural circuits of scores of communicating neurons.
"These fields were once thought to be an epiphenomenon, a 'bug' of sorts, occurring during neural communication," said Caltech neuroscientist Costas Anastassiou. But the work done by Anastassiou and his colleagues suggests that the fields do much more, and that they may, in fact, represent an additional form of neural communication.

"While active neurons give rise to extracellular fields, the same fields feed back to the neurons and alter their behavior," even though the neurons are not physically connected - a phenomenon known as ephaptic coupling. "So far, neural communication has been thought to occur at localized machines, termed synapses. Our work suggests an additional means of neural communication through the extracellular space independent of synapses."

Extracellular electric fields exist throughout the living brain, though they are particularly strong and robustly repetitive in specific brain regions such as the hippocampus, which is involved in memory formation, and the neocortex, the area where long-term memories are held. "The perpetual fluctuations of these extracellular fields are the hallmark of the living and behaving brain in all organisms, and their absence is a strong indicator of a deeply comatose, or even dead, brain," Anastassiou explains.

Previously, neurobiologists assumed that the fields were capable of affecting neural activity only during severe pathological conditions such as epileptic seizures, which induce very strong fields. Few studies, however, had actually assessed the impact of far weaker - but very common - non-epileptic fields. "The reason is simple," Anastassiou says. "It is very hard to conduct an in vivo experiment in the absence of extracellular fields," to observe what changes when the fields are not around. 

To get to grips with those effects, the team focused on strong but slowly oscillating fields, called local field potentials (LFP), that arise from neural circuits composed of just a few rat brain cells. Measuring those fields and their effects required positioning a cluster of tiny electrodes within a volume equivalent to that of a single cell body, and at distances of less than 50 millionths of a meter from one another.

An unexpected and surprising finding was how already very weak extracellular fields can alter neural activity. "We observed that fields as weak as one millivolt per millimeter robustly alter the firing of individual neurons, and increase the so-called 'spike-field coherence' [the synchronicity with which neurons fire with relationship to the field]. In the mammalian brain, we know that extracellular fields may easily exceed two to three millivolts per millimeter. Our findings suggest that under such conditions, this effect becomes significant."

Anastassiou speculates that understanding how these fields function could transform our understanding of how the brain does its work. "Increased spike-field coherency may substantially enhance the amount of information transmitted between neurons as well as increase its reliability. Moreover, it has been long known that brain activity patterns related to memory and navigation give rise to a robust LFP and enhanced spike-field coherency. We believe ephaptic coupling does not have one major effect, but instead contributes on many levels during intense brain processing."

He goes further, suggesting that understanding the origin and functionality of endogenous brain fields will lead to revelations regarding information processing at the brain's circuit level, likely where percepts and concepts arise.

Intriguingly, Anastassiou posits that external electric fields could have profound effects on the brain. "Physics dictates that any external field will impact the neural membrane. During epileptic seizures, pathological fields can be as strong as 100 millivolts per millimeter [and] such fields strongly entrain neural firing and give rise to super-synchronized states." And that, he adds, suggests that electric field activity from external fields in certain brain areas, during specific brain states, may have strong cognitive and behavioral effects.

Lending support to this controversial notion is an unrelated study, published in the open-access journal PLoS ONE, carried out by researchers at the University of Sydney in Australia. Their work suggests that we may be on the verge of being able to stimulate the brain into super-creative states via an "electric thinking cap." 

In the study, researchers Richard Chi and Allan Snyder found that participants who received electrical stimulation of the anterior temporal lobes were three times as likely to reach the fresh insight necessary to solve a difficult, unfamiliar problem than those in a control group.
According to the authors, our propensity to rigidly apply strategies and insights that have had previous success is a major bottleneck to making creative leaps in solving new problems. There is normally a cognitive tradeoff between the necessity of being fast at the familiar on one hand and being receptive to novelty on the other.

Chi and Snyder argue that we can modulate this tradeoff to our advantage by applying transcranial direct current stimulation (tDCS), a safe, non-invasive technique that temporarily increases or decreases excitability of populations of neurons. 

In particular, tDCS can be used to manipulate the competition between the left and right hemisphere by inhibiting and/or disinhibiting certain networks. Their findings are consistent with evidence that the right anterior temporal lobe is associated with insight or novel meaning and that inhibition of the left anterior temporal lobe can induce a cognitive style that is less top-down, less influenced by preconceptions.

While further studies involving brain stimulation in combination with neuroimaging are needed to elucidate the exact mechanisms leading to insight, Chi and Snyder can imagine a future when non-invasive brain stimulation is briefly employed for solving problems that have evaded traditional cognitive approaches.

Source: California Institute of Technology, University of Sydney

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How to Digitally Record/Video a UFO sighting:


Como registar digitalmente ou gravar um vídeo de um avistamento de um UFO:




Stabilize the camera on a tripod. If there is no tripod, then set it on top of a stable, flat surface. If that is not possible lean against a wall to stabilize your body and prevent the camera from filming in a shaky, unsteady manner.

Estabilize a camera com um tripé. Se não tiver um tripé, então coloque-a em cima de uma superfície estável. Se não for possível, então encoste-se a uma parede para estabilizar o corpo e evitar que a camera registe de maneira tremida e instável.

Provide visual reference points for comparison. This includes the horizon, treetops, lampposts, houses, and geographical landmarks (i.e., Horsetooth Reservoir, Mt. Adams, etc.) Provide this in the video whenever is appropriate and doesn’t detract from what your focus is, the UFO.

Forneça pontos visuais de referência para comparação. Isso inclui o horizonte, cimo das árvores, postes de iluminação, pontos de referência geográficos (como o Reservatório de Horsetooth, Mone Adams, etc) Forneça esses pontos no vídeo sempre que for apropriado e não se distraia do que é o seu foco, o UFO/a Nave.

Narrate your videotape. Provide details of the date, time, location, and direction (N,S,E,W) you are looking in. Provide your observations on the weather, including approximate temperature, windspeed, any visible cloud cover or noticeable weather anomalies or events. Narrate on the shape, size, color, movements, approximate altitude of the UFO, etc and what it appears to be doing. Also include any unusual physical, psychological or emotional sensations you might have. Narrate any visual reference points on camera so they correlate with what the viewer will see, and thereby will be better able to understand.

Faça a narração do vídeo. Forneça pormenores sobre a data, hora, local e direcção (Norte, Sul, Este, Oeste) que está a observar. Faça observações sobre as condições atmosféricas, incluindo a temperatura aproximada, velocidade do vento, quantidade de nuvens, anomalias ou acontecimentos meteorológicos evidentes. Descreva a forma, o tamanho, a cor, os movimentos, a altitude aproximada onde se encontra o UFO/nave, etc e o que aparenta estar a fazer. Inclua também quaisquer aspectos pouco habituais de sensações físicas, psicológicas ou emocionais que possa ter. Faça a narração de todos os pontos de referência visual que o espectador irá ver e que, deste modo, será capaz de compreender melhor.

Be persistent and consistent. Return to the scene to videotape and record at this same location. If you have been successful once, the UFO sightings may be occurring in this region regularly, perhaps for specific reasons unknown, and you may be successful again. You may also wish to return to the same location at a different time of day (daylight hours) for better orientation and reference. Film just a minute or two under “normal” circumstances for comparison. Write down what you remember immediately after. As soon as you are done recording the experience/event, immediately write down your impressions, memories, thoughts, emotions, etc. so it is on the record in writing. If there were other witnesses, have them independently record their own impressions, thoughts, etc. Include in this exercise any drawings, sketches, or diagrams. Make sure you date and sign your documentation.

Seja persistente e não contraditório. Volte ao local da cena e registe o mesmo local. Se foi bem sucedido uma vez, pode ser que nessa região ocorram avistamentos de UFOs/naves com regularidade, talvez por razões específicas desconhecidas, e talvez possa ser novamente bem sucedido. Pode também desejar voltar ao mesmo lugar a horas diferentes do dia (durante as horas de luz)para ter uma orientação e referência melhor. Filme apenas um ,inuto ou dois em circunstâncias “normais” para ter um termo de comparação. Escreva tudo o que viu imediatamente após o acontecimento. Logo após ter feito o registo da experiência/acontecimento, escreva imediatamente as impressões, memórias, pensamentos, emoções, etc para que fiquem registadas por escrito. Se houver outras testemunhas, peça-lhes para registar independentemente as suas próprias impressões, pensamentos, etc. Inclua quaisquer desenhos, esbolos, diagramas. Certifique-se que data e assina o seu documento/testemunho.

Always be prepared. Have a digital camera or better yet a video camera with you, charged and ready to go, at all times. Make sure you know how to use your camera (and your cell phone video/photo camera) quickly and properly. These events can occur suddenly, unexpectedly, and often quite randomly, so you will need to be prepared.

Esteja sempre preparado, Tenha sempre uma camera digital, melhor ainda, uma camera vídeo consigo, carregada e pronta a usar sempre que necessário. Certifique-se que sabe como lidar com a sua camera (ou com o seu celular/camera fotográfica) rápida e adequadamente. Esses acontecimentos podem acontecer súbita e inesperadamente e, por vezes, acidentalmente, por isso, necessita estar preparado.

Look up. Be prepared. Report. Share.

Olhe para cima, Esteja preparado, Relate, Partilhe.

MUFON.COM

ESOTERIC



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